Palacio Domain - Stylish European Luxury Boutique Hotel is a boutique property in Safed, and is set in a renovated 12th-century building. The hotel is in the heart of Safed's artists neighborhood. Palacio Domain - Stylish European Luxury Boutique Hotel is near the main art galleries and ancient synagogues of Safed's Old City. It is a great starting place for exploring the Galilee area, including Mount Hermon, Tiberias and the Sea of Galilee.