The Uffizi Gallery is one of the richest museums in the world. Its collections chart the evolution of Italian painting from the Primitives to the 17C. The museum is set in the former seat of Florence's Medici bureaucrats. Built by Vasari in 1560 in late-Renaissance style, a long square is delineated by two parallel galleries. Among the masterpieces on display, do not miss Botticelli's Birth of Venus and Spring, Leonardo da Vinci's Annunciation or Michael Angelo's Doni Tondo.