221 Guesthouse enjoys a location in Pretoria, 4 miles from Pretoria Country Club and 4.7 miles from Voortrekker Monument. 2 miles from University of Pretoria and 2.7 miles from Union Buildings, the property provides an outdoor swimming pool and a terrace. The bed and breakfast features rooms with air conditioning, free private parking, and free Wifi.
At the bed and breakfast, units are fitted with a wardrobe, a TV, a private bathroom, bed linen, and towels. There's also a dressing room in some of the units.
There is an on-site bar.
Rietvlei Nature Reserve is 12 miles from the bed and breakfast, while Irene Country Club is 12 miles from the property. The nearest airport is Wonderboom Airport, 8.7 miles from 221 Guesthouse.