Located off the Homer Adams Parkway in Alton, Illinois, this hotel is a 15-minute drive from the Lewis and Clark Historic Site. It features an indoor pool and free Wi-Fi. The traditional guest rooms at Comfort Inn Alton near I-255 Alton include a microwave and refrigerator. They are equipped with cable TV. Hot waffles are part of the breakfast served every morning at this Alton hotel. The front desk is open 24 hours a day and a business center is located off of the lobby. The Argosy Casino is a 10-minute drive from the Alton Comfort Inn Alton near I-255. Downtown St. Louis is 20 miles from the property.